Pabrinex IM High Potency 7ml (1 x 5ml, 1 x 2ml) Ampoule POM x10

Concentrate for Solution for Infusion

Therapeutic indications
Pabrinex is indicated in adults and children for rapid therapy of severe depletion or malabsorption of the water soluble vitamins B and C:
• particularly in alcoholism, where a severe depletion of thiamine can lead to Wernicke's encephalopathy
• after acute infections
• post-operatively
•in psychiatric states
Also used to maintain levels of vitamin B and C in patients on chronic intermittent haemodialysis.

Features

Nature and contents of container
• Pabrinex Intravenous High Potency, Concentrate for Solution for Infusion is supplied in pairs of amber glass ampoules of 5 ml or 10 ml. Packs contain either, six or ten pairs of 5 ml ampoules, or five pairs of 10 ml ampoules.

Special precautions for storage
• Do not store above 25°C. Keep the container in the outer carton. Do not freeze.
• For storage conditions after dilution of the medicinal product, see section 6.3.

Shelf life
• Before opening: 24 months.
• After opening: Chemical and physical in-use stability of intravenous high potency vitamins B and C has been demonstrated in the following intravenous infusion fluids for the number of hours stated in the table below, at room temperature:

Intravenous infusion fluid In the light
Glucose 5% 7 hours
Physiological saline (sodium chloride 0.9%) 7 hours
Glucose 4.3% with sodium chloride 0.18% 4 hours
Glucose 5% with potassium chloride 0.3% 4 hours
Sodium lactate M/6 7 hours

Although no further specific data are available, the solutions are expected to be stable for longer periods when protected from light.

From a microbiological point of view, the product should be used immediately. If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2 to 8°C, unless dilution has taken place in controlled and validated aseptic conditions.

The diluted solutions should not be frozen.


Note: As this item requires to be stored between 2 and 8°C, it is considered cold chain supply and so will not be shipped to customers on a Friday.